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Tell your doctor right away if you have any serious side effectsincludingnausea/vomiting that doesn’t stopstomach/abdominal painyellowing eyes/skindark urinesigns of infectionsuch as sore throat that doesn’t go awayfeverchillscoughsigns of kidney problemssuch as pain in the side/back/abdomenpainful urinationblood in the urinechange in the amount of urinejoint painsuch as big toe paineasy bruising/bleeding.

Hypokalemia may develop with thiazide therapyespecially with brisk diuresiswhen severe cirrhosis is presentor during concomitant use of corticosteroidsACTHamphotericin B or after prolonged thiazide therapyHoweverhypokalemia of this type is usually prevented by the triamterene component of MAXZIDEtriamterene and hydrochlorothiazide

The thiazides may decrease arterial responsiveness to norepinephrineThis diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic useThiazides have also been shown to increase the responsiveness to tubocurarine.

This medicine may be prescribed for other usesask your doctor or pharmacist for more information.

Triamterene may be used alone or with other diureticseither for its added diuretic effect or its potassium-sparing potentialIt also promotes increased diuresis when patients prove resistant or only partially responsive to thiazides or other diuretics because of secondary hyperaldosteronism.

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