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DATA COLLECTION AND ANALYSISData were independently extractedFor homogeneous dichotomous data the random effects relative riskRRthe 95confidence intervalsCIandwhere appropriatethe number needed to treatNNTwere calculated on an intention-to-treat basisFor continuous data the reviewers calculated weighted mean differences.

While olanzapine demonstrated anticholinergic activity in vitroexperience during the clinical trials revealed a low incidence of related eventsHoweveras clinical experience with olanzapine in patients with concomitant illness is limitedcaution is advised when prescribing for patients with prostatic hypertrophyor paralytic ileus and related conditions.

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