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The dosage is based on your medical condition and response to treatmentYour doctor may gradually increase your doseFollow your doctor’s instructions carefully.

Amlodipine is a calcium channel blockerIt blocks special channels on the surface of cells called calcium channelsthrough which calcium particles normally enterWhen calcium enter the cells in the muscles of blood vessel wallsthis causes contractionBy reducing the flow of calcium into the cellsamlodipine prevents the blood vessel walls from contractingthus lowering the blood pressure for patients with hypertension and helping to make it easier for patients with heart problems to pump blood around the body.

SildenafilWhen amlodipine and sildenafil were used in combinationeach agent independently exerted its own blood pressure lowering effectsee Drug Interactions7.1

TelmisartanMicardisand AmlodipineNorvascFactorial Design Study for the Treatment of Hypertension.

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