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May increase prograf whole blood trough concentrations and increase the risk of serious adverse reactions e.

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A very serious allergic reaction to this drug is rareHoweverget medical help right away if you notice any symptoms of a serious allergic reactionincludingrashitching/swellingespecially of the face/tongue/throatsevere dizzinesstrouble breathing.

ISMP Canada gratefully acknowledges the expert review of this article byin alphabetical orderPatti CornishRPhBScPhmPatient Safety ServiceSunnybrook Health Sciences CentreJennifer HarrisonBScPhmMScPharmacy Clinical Site LeaderUniversity Health NetworkNicola RosaasenBScBSPPharmacistSaskatchewan Transplant ProgramJeffrey SchiffMDFRCPCMulti-Organ Transplant ProgramToronto General HospitalJohn W SendersPhDProfessor EmeritusUniversity of TorontoAnita WongBScPharmRexall Outpatient PharmacyUniversity of Alberta Hospitaland Ken WouBSc(Pharmpharmacy consultant.

Pediatric liver transplantation patients without pre-existing renal or hepatic dysfunction have required and tolerated higher doses than adults to achieve similar blood concentrations.

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