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You may be taking other medicines that should not be taken at the same timeTaking sevelamer can make it harder for your body to absorb certain drugsmaking them less effective:

Do not use Renvela or Renagel if you have a history of bowel obstruction or if you are allergic to sevelamer carbonate or sevelamer hydrochloride or to any of the ingredients in Renvela or RenagelTalk to your doctor if you have had difficulty swallowing or swallowing disordersor if you have had digestive tract surgery or other digestive disordersincluding severe constipationThe most common side effects with sevelamer include vomitingnauseadiarrheaupset stomachabdominal painflatulenceand constipationCases of itchingrashfecal impaction andless commonlyslow bowel activitybowel obstructionand bowel perforation have been reportedUncommon cases of difficulty swallowing the Renagel or Renvela tablet have been reportedTalk to your doctor if you have difficulty swallowing medicines in tablet formRenvela powder for oral suspension may be considered by your doctor if you have a history of difficulty swallowingYour doctor should monitor bicarbonate and chloride blood levelsReduced vitamins DEand Kclotting factorsand folic acid blood levels may be followed by your doctorTalk to your doctor when taking sevelamer with other medicationsPromptly contact your doctor if you experience severe abdominal painnew or worsening constipationor other severe intestinal symptoms while on sevelamerTake sevelamer with meals and adhere to your prescribed diet.

In interaction studies in healthy volunteersRenagel had no effect on the bioavailability of digoxinwarfarinenalapril or metoprolol.

Check with your doctor immediately if any of the following side effects occur while taking sevelamer:

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